Hormone Replacement Therapy (HRT)
Posted by Emily Thompson on Sep 2nd 2020
HRT Bases
*Please note that we no longer carry bases at Total Pharmacy Supply, but we still offer a vast selection of supplies to support your pharmacy in all its compounding needs.
HRT Botanical is an oil-in-water, light cream with a lotion consistency. The all natural ingredients and antioxidants provide sustained skin penetration while remaining cosmetically elegant. HRT Botanical can be used for high lipophilic Active Pharmaceutical Ingredient (API) concentrations and vaginal preparations.
HRT Heavy is a heavier cream base than HRT Botanical. It provides slightly deeper skin penetration, making it ideal for male and female hormone restoration. For intravaginal or topical formulations, HRT Heavy is compatible with all hormone APIs.
Published Stability/Potency Studies – Beyond-Use-Date (BUD)
|
Active Pharmaceutical Ingredient (API) |
BUD |
| Estriol 1% |
120 Days |
| Estradiol 1% |
90 Days |
| Progesterone 20% |
180 Days |
| Testosterone 5% |
180 Days |
Formula ideas
|
Estriol 1% Topical Cream |
30 ml |
| Estriol, USP (micronized) powder |
0.3 g |
| Base, HRT Botanical |
QS 30 ml |
|
Estradiol 1% Topical Cream |
30ml |
| Estradiol, USP (micronized) powder |
0.3 g |
| Base, HRT Botanical |
QS 30 ml |
|
Progesterone 20% Topical Cream |
30ml |
| Progesterone, USP (micronized) powder |
6 g |
| Base, HRT Heavy |
QS 30 ml |
|
Testosterone 5% Topical Cream |
30ml |
| Testosterone, USP (micronized) powder |
1.5 g |
| Base, HRT Heavy |
QS 30 ml |
Packaging Tips
Topi-Click® is a metered dose dispenser that's easy to use and helps achieve maximum medication compliance. It is designed specifically for the physician's patients that use custom compounded topical prescriptions. Each quarter turn of the base dispenses approximately 0.25ml of product. Allows direct application without dispensing on hands.